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Fas has homologous region referred to as "death structure domain" which functions to transduct apoptosis signal, activate a series of cysteine protease, and finally lead to cell death.
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Either constitutively active or signal activated PP2A may modulate IKKβ activity.
A different type of signal activates each pathway.
The START signal activates the CINM and it acknowledges the CU with READY signal.
In the SCN, the photic signal activates mTOR signaling and promotes the translation of VIP by repressing 4E-BP1.
When an interaction is required, this signal activates a social affordance.
As such, DR* is the signal activating, i.e., transcriptionally regulating, the expression of the pro-inflammatory genes.
Therefore, we modeled this mechanism by a cell-size signal activating Cln3.
The signal activates the serine/threonine kinases termed MAPKKK, which phosphorylate the MAPK kinases (MAPKK).
DDR signal activates a rapid signal transduction pathway, regulating the cell fate based on the damaged cell condition.
Thus, extracellular Hsps act as a "danger signal," activating immune-competent cells through LPS TLR4/CD14-dependent signaling [ 103].
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