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Hence, if the politically decisive individual is entitled to a smaller-than-average ω i <1 portion of the economy's non-labor income, the policy-choice problem effectively features a smaller β and, as shown when establishing the sign of expression (6), this implies a preference for more redistribution.
A total of 17 members of this family were detected without sign of expression modulation.
Other genes encoding enzymes with known antioxidant activity, such as catalases and ascorbate peroxidases were found in our survey, but without sign of expression modulation.
Rather, the absence of any detectable sign of expression conservation in this co-module suggests that different genes are involved in olfactory function in mouse and human.
Peroxibase [ 44] reports 19 records of soybean peroxidases with homology to respiratory burst oxidases but none of them were found with a sign of expression modulation in our study.
Further improvements to the BioQuali plugin will consist in adding functionalities related to sign inference in oriented but unsigned regulatory networks [ 17], incorporating the zero value as a fourth sign of expression change or regulation, adding the possibility of representing an interaction as a boolean function, and building a user-friendly interface for experimental design.
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Why do the "absent" genes, with expression pattern otherwise indistinguishable from the background noise suddenly show signs of expression consistent with that of reliably detectable genes?
AnoTExcel also presents one cluster with signs of expression belonging to the I superfamily.
Interestingly, we discovered two organ-specific co-modules with no detectable signs of expression conservation (γ = 0), i.e., the ovary-specific and the olfactory-specific co-module.
Evolutionary conserved exons were detected using the Conservation Index score [ 26] (Table 2) which measures the evolutionary distance at which an exon is both genomically conserved and shows signs of expression.
However, we did not find signs of expression (i.e. associated ESTs) for any of these putative genes, and some of them also appeared not to code for full-length proteins, suggesting that they represent non-functional DNA inserted into the nuclear genome, therefore they will not be further considered here.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com