Data collected included demographics, initial vital signs, duration of symptoms, body part affected, presence of lymphangitis if mentioned, white blood cell count, absolute neutrophil count, percent bandaemia present, haemoglobin, haematocrit, initial glucose, erythrocyte sedimentation rate and C-reactive protein.
The original referral forms were searched for information on methods of sampling, clinical signs, duration of signs, and nutritional status.
(The abbreviation ABCD2 is derived from the measures of age, blood pressure, clinical signs, duration and diabetes, on which the score is based).
There were conflicting but mainly negative results regarding the influence of baseline pain severity, neurological deficit, nerve root tension signs, duration of symptoms and radiological findings on outcome.
Severe clinical signs, duration of clinical signs for more than 3 months per year, and insufficient management with symptomatic therapy, due to side effects to the drugs used and/or poor owner compliance, justify in most cases allergy testing.
In addition, based on their infiltrative nature and location within the brainstem, DIPGs are often diagnosed clinically based on a combination of neurological signs, duration of symptoms and specific neuro-imaging findings.
In line with the findings of a recent meta-analysis [ 80], positive symptoms of the GRAS patients do not influence higher cognitive function or basic cognition/fine motor performance, whilst negative symptoms, catatonic signs, duration of disease and antipsychotic medication have a significant effect on both.
Documented fields included first author, publication year, symptoms and signs, duration of symptoms until diagnosis, age at diagnosis, race, gender, histology, size of tumour, location, presence of metastases, type of surgery, type of radiotherapy, radiotherapy response, type of chemotherapy, chemo-response, tumour recurrence, observation time, and outcome.
Just as slight variations in the pitch and volume of one's voice convey information in a spoken language, fluent speakers of ASL can pick up small differences in a sign's duration, range of motion, and body language.
Clinical parameters were assessed and used in the analysis: EAE, incidence of EAE; ONS, onset of EAE (day p.i. of first clinical sign); DUR, duration of EAE (number of days subjects showed clinical signs of EAE); MAX, maximum EAE score during the experiment; SUM, sum of all scores during the experiment; s35, EAE score on day 35 post immunization (p.i).
