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The Stroke Adapted Sickness Impact Profile measures sickness specific quality of life in stroke patients and is a modified version of the 136-item SIP.
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The following definitions were used: Sick-leave period: the length of time covered by a specific sickness certificate.
General reasons for dropout were reported (no time and sickness) but not specific attributes.
We further studied the incidence of a specific sickness absence pattern labelled as "normal" and "abnormal".
Table 2 shows associations between psychiatric sickness absence and specific causes of mortality.
In rodents, damage to the vagus nerve attenuates specific sickness behaviors, including changes in motivation (14) and social behavior (15).
This strategy eliminates potential confounding factors due to general sickness caused by specific RNAi treatment, which might result in nematodes exhibiting decreased survival during infection.
In the present investigation, our aim was to extend that prior finding by testing associations between psychiatric sickness absence and specific causes of death.
Longitudinal data are needed to describe the patterns of sickness absence in specific diagnostic groups and to provide a better understanding of pathogenesis.
However, to our knowledge, the association between psychiatric sickness absence and specific causes of death has been examined in only a single investigation based on the British Whitehall II study.
In humans, hyperactivity of neuroendocrine pathways and disrupted neurotransmitter metabolism have been observed in clinically depressed people (Hayley et al., 2005) and in patients undergoing IFN-α therapy, where they correlate with development of specific sickness symptoms (Capuron and Miller, 2004).
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