Inflammation is associated with psychological, emotional, and behavioral disturbance, known as sickness behavior.
It is well known that systemic inflammation, induced by endotoxin or proinflammatory cytokines, can induce CNS-mediated behavioral responses known collectively as sickness behavior (12).
In healthy mammals, systemic infections typically engender a set of behavioral, psychological, and physiological changes collectively known as "sickness behavior".
In healthy mammals, systemic infection triggers a set of behavioral, psychological, and physiological changes collectively known as "sickness behavior" (1,2).
Therefore, our understanding of human sickness behavior remains equivocal.
... That could make the behavior evolutionarily advantageous". The individual advantages of sickness behavior are well known.
Following administration of LPS, all cattle displayed increased sickness behavior beginning at 0.5 h, with heifers on average displaying less sickness behavior than bulls.
Background: Enhanced pain sensitivity is a component of sickness behavior in experimental animals.
Factors that influence subjective health ratings (e.g. pain, tiredness, lack of energy) resemble immune activated sickness behavior.
Central administration of insulin-like growth factor-I (IGF-I) attenuates sickness behavior in response to the cytokine inducer lipopolysaccharide.
Proinflammatory cytokines induce sickness behavior, a constellation of symptoms that bears a strong similarity to those of depression.
