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The current data set contains 23 pre-inoculation (healthy) samples and 34 post-inoculation (sick) samples.
We used edgeR to identify differentially expressed genes between healthy and sick samples from the expression estimates computed with each mapping method.
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Old-school Votomatic booths will make you feel sick, and sampled drum patterns will make you feel sicker just a different kind of ill.
Since workers aged over 45 years more frequently call in sick, our sample still seems to be representative [ 3, 58].
Rheumatic disease and psychiatric disease were reported almost twice as often by the newly sick listed sample (rheumatic disease: 5.3% newly sick listed, 2.8% general population; psychiatric disease: 10.4% newly sick listed, 5.5% general population).
There was a significantly higher proportion reporting most chronic disease groups among the newly sick-listed sample compared with the general population sample.
The newly sick-listed sample and a randomized general population sample (n = 7,984) received a questionnaire (participation rates: 54% and 50%).To assess the burden of self-reported chronic diseases, standardized incidence ratios (SIR) were calculated.
Finally, the newly sick-listed sample was composed solely of employed individuals while the general population sample was a random sample of the total population.
The expected number of cases was calculated for the sick-listed sample using proportions derived from the randomized general population sample results in each group [ 35].
#Standardized incidence ratios (SIR) for chronic disease in the newly sick-listed sample are shown.
If the SIR was 1.0 the incidence in the newly sick-listed sample equalled that of the general population.
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