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Whereas shuffling of genes within this cluster can be detected (e.g., clone HF10_29C11; Figures 2 and 3; [41]), this process appears to be less frequent than horizontal transfer of the entire cluster.
We will consider "asexual" those species in which the shuffling of genes does not occur.
Secondly, the shuffling of genes brought about by genetic recombination is a major engine of genetic variation.
Modular shuffling of genes is likely mediated by recombination between PeSLs, and this genetic exchange likely proceeds through small circular DNA intermediates formed by the recombination event.
What is the point of creating, by the shuffling of genes, a variety of genetic combinations that will be tested by natural selection?
Thus, it appears that all of the operons examined evolved from a common ancestral eight-gene cluster without shuffling of genes within or between operons.
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Many proteins are the result of the shuffling of gene segments.
Novel vectors for cloning and shuffling of gene cassettes based on minireplicon of broad-host-range RA3 plasmid from IncU incompatibility group were constructed.
In contrast, genome comparisons of virulent and non-virulent Francisella tularensis showed that transposon mediated recombination and shuffling of gene order occurred in the pathogenic strains rather than the non-pathogenic strain [7].
In contrast to this study, genome comparisons of virulent and non-virulent Francisella tularensis showed that transposon mediated recombination and shuffling of gene order occurred in the pathogenic strains rather than the non-pathogenic strain [7], also they did not find deletions associated with transposon mediated recombination as seen in R. peacockii.
The circular β-ζ permutation may be explained both by gene duplication or shuffling of gene fragments.
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