Sentence examples for shuffling of exons from inspiring English sources

Comparative analysis of the exon sequence does not support the idea that the SPARC gene has evolved by shuffling of exons from other Ca2+-binding proteins.

Based on our data one could suggest that there are limitations to shuffling of exons that code functional protein sites.

Genomes are shaped by a series of processes involving substitutions, insertions, deletions, transpositions, shuffling of exons or chromosomes, lateral gene transfer, gene fusion or fission, de novo origination, and gene and genome duplications.

42 The prediction of the presence of different domains in the protein was possible because of the gene sequencing, determining that each domain was encoded by separate exons or group of them and suggesting that the LDLr might have evolved through shuffling of exons from other genes, because it has parts similar to unrelated proteins.

These observations concur with the concept of exon shuffling, wherein exons encode structural modules of proteins and the loss and gain of introns and the shuffling of exons via recombination events contribute to the complexity of modern day proteomes.

These observations concur with the concept of exon shuffling, wherein exons encode structural modules of proteins and that throughout the evolution the loss and gain of introns and the shuffling of exons via recombination events contributes towards the complexity of modern day proteomes [ 70, 72].

Added variability for UBA is produced by shuffling of exon 2 onto different exon 3 and downstream regions through recombination occurring in intron 2 [ 4].

Aside from the mutational loss of reactions (which may be slow for reactions in a highly constrained reaction set), new enzymes can be created through gene duplication and subsequent sequence divergence, as well as through recombination and shuffling of domains and exons [ 91- 94].

The base composition of these putative ESEs is skewed relative to overall exon base frequencies, with the hexamers being composed of 48% A, 14% C, 25% G, and 13% T. Therefore, we also examined the base composition and expected number (through random shuffling of exon sequences) of ESE sites in each flanking exon.

For example, although experimentally not proven, exon shuffling of primary mRNA transcripts has been suggested as a mechanism to account for active site variation in amino acid sequences of venom gland serine proteases in the snake Macrovipera schweizeri (Milos viper) [ 30].

For example, a better permutation may shuffle groups of exons (genes), rather than individual exons.