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The nucleus of these cells seem to have increased evidence of nuclear membrane breakdown with chromatin disorganization and severely shrunken appearance of cell death (Fig. 14c).
Visual observation revealed that the CALB-positive neurons of vehicle treated R6/2 mice exhibited a previously described shrunken appearance [3] and were of apparently smaller size than in wild-type mice.
Electron microscopical analysis confirmed the presence of degenerating neurons with darkened and shrunken appearance in the striatum (Fig. 5F) and in the motor cortex (Fig. 5M) when compared with intact light appearing neurons in the respective areas of DMF treated mice (Fig. 5E,L).
Moreover, the N2 gas plasma treated influenza viruses displayed a shrunken appearance.
The islets displayed a shrunken appearance due to degranulation of cells.
The TUNEL-positive nuclei did not display the characteristic shrunken appearance expected for an apoptotic cell, again emphasizing the need to corroborate staining results with morphological observations.
Similar(51)
But the heart was wasted and shrunken in appearance.
In contrast, other European leaders appeared shrunken and reduced.
Many neurons appeared shrunken and electron-dense.
They appeared shrunken with small pyknotic nuclei.
This cell became shrunken and its plasma had a ground-glass appearance.
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CEO of Professional Science Editing for Scientists @ prosciediting.com