"The intense and early discounting will negate the power of runway shows to drive fashion in both creative and commercial terms," Ms. Buccini said.
For Nox4, it has been shown that knockdown leads to decreased MAPK (mitogen-activated protein kinase) activity in various cell types [ 23, 24] and Nox4-induced activation of p38 was shown to drive differentiation of murine cardiomyocytes [ 25].
BMP4/Smad signaling has been shown to drive expression of inhibitor of differentiation (Id) genes, and forced expression of Id genes in ES cells is sufficient for maintaining self-renewal in the absence of BMP4 [8].
In other aspects of my life, I show plenty of drive.
The active form of Y705F-STAT3 washownwn to drive the expression of many genes important in oncogenesis, cell cycle control and the immune response.
Soluble metals have been shown to drive many of the pulmonary effects of ROFA (Dreher et al. 1997; Kodavanti et al. 1998; Rice et al. 2001).
De novo transcription has been shown to drive rhythmicity of approximately 20 30% of all cycling genes (Koike et al., 2012; Menet et al., 2012), which illustrates the importance of post-transcriptional regulation in shaping the circadian transcriptome.
In turn, IL-12-induced activation of STAT4 has been shown to drive the production of Th1 and Th17 rather than Th2 cells, and a Th1/Th17 mediated inflammatory response is a hallmark of RA (19).
EWS/FLI1 has been shown to drive proliferation of Ewing's sarcoma cells and block most of the differentiation potential except for a partial neural gene expression program.
Many oncogenic events were shown to drive proliferation of these myeloid cells (Tefferi and Gilliland, 2007).
Across many experiments, these striatal value signals have been shown to drive learning of cognitive control for action selection and nondeclarative learning12,14,15,16,17.
