The pathology shows dysfunctions and cell death of Purkinje cells in the cerebellum and motor neurons in the spinal cord.
And as the book progresses, Solanka emerges as a strangely synthetic character, hastily assembled out of bits and pieces of fable, metaphor and television talk-show dysfunction.
Studies in primary burning mouth syndrome have shown dysfunction of the nigrostriatal dopaminergic pathway [1, 3, 4].
We found that hippocampal signal was significantly diminished in elderly subjects with memory decline compared to age-matched controls, and different subjects showed dysfunction in different subregions.
In patients with OCD displaying washing and checking compulsions, neuroimaging studies have shown dysfunction of orbitofrontal, cingular and temporal cortices as well as of the caudate nucleus [46], [47].
In patients suffering from GTS without psychiatric co-morbidities, structural and functional neuroimaging studies as well as transcranial magnetic stimulation studies have shown dysfunction of premotor, sensorimotor, dorsal parietal, dorsolateral prefrontal and cingulated and insular cortical areas [42] [44].
Patients with IBS show dysfunction in the brain gut axis, including anxiety, depression, gut dysmotility and visceral hypersensitivity.
As well as impairments in lung function, smoke-exposed mice show dysfunction and fibre-type switching in the soleus muscle.
We hypothesized that ACUP on GB 34 has an effect on brain areas that are known to show dysfunction due to nigral dopamine depletion.
None of the 19 horses that did not display abnormal respiratory noise during exercise showed dysfunction of the upper airway during an endoscopic examination at rest.
