The dorsal striatum, a region involved in learning from mistakes, also showed diminished activity.
Microinjection results for the A-series show diminished activity for the AM5, AM6 and, AM8 AM8 constructs and normal activity in the others (Figure 5B).
Furthermore, tyrosine hydroxylase (TH), the rate-limiting enzyme of catecholamine biosynthesis showed diminished activity and newer findings indicate, that TH gene expression was also reduced after antidepressant treatment [47], [48].
Some VDAC1-based peptides showed diminished activity.
The obese group with BED showed diminished activity in the ventromedial prefrontal cortex (vmPFC), inferior frontal gyrus (IFG) and insula.
The EMG of the external anal sphincter was normal in all the 9 patients (fig. 2) while the levator ani showed diminished activity in 4 of the 6 constipated patients (fig. 3).
Although the overall number of neuroimaging studies in pathological gamblers is still modest, fMRI studies have consistently shown diminished activity in the mesolimbic pathways in pathological gamblers comprising the ventral striatum, amygdala, and VMPFC when problem gamblers are dealing with reward and loss processing, but not when they are in a gambling situation.
It shows diminished catalytic activity and is intracellular or secreted.
Membranes from BFA-treated cells did not show diminished lipidation activity, nor did BFA mitigate or enhance the effect of H89 treatment on lipidation activity.
Our data showed diminished gamma activity at the amygdala, OFC, and insula in response to sad faces during early emotion perception in MDD patients.
Furthermore, the proteases cathepsin B and cathepsin D in patients with IBM showed diminished protease activity when compared to those in controls.
