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The present work shows a rational method for the development of the freezing step of a freeze-drying cycle.
Thus, the outcome of the present study clearly shows a rational coordination in the time-based onset phase of tongue pressure and pharyngeal pressure in the voluntary swallowing of saliva.
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In the present article, the luminal degradation of prodrugs was kinetically assessed to understand crucial factors in the intestinal absorption of prodrugs and to show a rational development procedure.
In this framework the present paper shows how a rational choice of the updating parameters and of the objective function can support the model optimization taking into account the ultimate objectives of the analysis, namely the setting of a reliable model for the assessment of the seismic performance of the structure in the linear regime.
This work shows that a rational design of functionalized MOF is a feasible way to improve the carbon dioxide/methane separation efficiency and to provide helpful information for future MOF preparation and applications.
In conclusion, the review shows that a rational utilitarian framework does not adequately encompass interpersonal interactions during organ donation.
He is no mere screen icon, but a real actor with a gift for engaging our sympathy and showing a naturally rational mind disordered by grief, murder and the hollow insufficiency of revenge.
The results show that a rational design applied to cationic double chain surfactants might serve as a promising strategy for the development of safe cationic vesicular systems.
Altogether, our findings show how a rational structure-based drug design approach coupled to cell-based drug evaluation strategies can be applied in medicinal chemistry to identify new agents targeting a given oncogenic-dependency setting.
In summary, these results show that a rational modification in the composition and structure of the nanoparticles, using safe materials, increases the prospects of their usefulness for mucosal protein delivery and transport.
We have shown through a rational design, synthesis and X-ray structural analyses of a set of aldehydes that o-methoxybenzaldehydes tend to associate in a centrosymmetric fashion, akin to the carboxylic acids, to give rise to a dimer motif II, which derives stabilization from four C H⋯O hydrogen bonds in addition to a dipole dipole interaction.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com