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The sequence of terraces of the River Thames in southeast England has previously been shown to span the period from the earliest Pleistocene to the present.
By sequential deletion of the HPO 5′-flanking region, the minimal promoter of the HPO gene was shown to span positions −22 to +42 relative to the transcriptional start point.
Since LTR variation rates were shown to span a nearly 6-fold range, LTR-RT insertion time dating that relies on a very general and approximate substitution rate is prone to severe errors.
Regions in the double-domain A3G protein that are important for HIV-1 Vif-mediated degradation have been shown to span both the amino- and the carboxyl-terminal domains of A3G.
One of the most interesting features of Shal/Kv4 currents are their variable inactivation rates, as shown to span three orders of magnitude in Drosophila neurons [25], the regulation of these biophysical properties [31], [49], and their more recently reported activity-dependent local trafficking [50].
Additionally, the phenotypically variable Carychium shell was shown to span a wide range of shell dimension and proportions, encompassing three morphospecies.
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The Sirt-2 gene was shown to regulate life span in yeast; increased dosage extended life span, and loss of function shortened it [ 128].
As a positive control, mianserin, which was previously shown to extend life span in C. elegans under similar conditions [22] also significantly extended mean life span by 35.9% (mean life span 27.1 days, n = 4 experiments, p = 0.00001, total 637 worms).
The discovery marks the first time a drug has been shown to lengthen life span in mammals, even when administered late in life.
Many genes that were initially shown to influence life span have turned out to be involved in DNA damage repair and protection.
I know that playing video games lowers sleep quality and memory in young teens, causes visible changes to the risk and reward processing centers of the brain, and has been shown to decrease attention span or increase it but definitely to alter it.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com