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But we see the importance of Royal Mail's modernisation programme, which is the cause of all this, and if strikes can be shown to be targeted at this, then we can see a justification for it.' Private operators such as TNT and Business Post, which process bulk mail, are unable to claim compensation under existing regulations.
These three P4Hs are shown to be targeted to the secretory pathway, where P4H5 forms dimers with P4H2 and P4H13.
As proof of concept, GPCR cell surface proteins are shown to be targeted specifically using multivalent ligands.
SMAD7 is shown to be targeted for polyubiquitination by ARKADIA and RNF12 (Koinuma et al., 2003; Liu et al., 2006; Zhang et al., 2012a; Zhang et al., 2012b).
The methods of Prony, Pisarenko, and MUltiple SIgnal Classification (MUSIC) are next shown to be targeted at analyzing signals with sparse frequency domain representations.
The enhanced antibody response induced by the AS04 vaccine formulation (1.6 4.1-fold 1.6 4.1-foldand humans was shown to be targeted to functinnal neutralising L1 VLP16 and L1 VLP18 epitopes as assessed by V5/J4 specific ELISAs or HPV16 and HPV18 pseudo-neutralization assays.
Virtually all aspects of TNFR signaling have been shown to be targeted by viruses in an attempt to escape immune surveillance [63].
In some cases the respective enzymes have been shown to be targeted into the mitochondria by fusing the presequences to GFP (C. Rio Bartulos, personal communication).
Because IL-12 plays a central role in protection from diverse intracellular pathogens, IL-12 has, itself, been shown to be targeted by HCV [39].
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Both the 30S and the 50S ribosomal subunits have been shown to be "targets of targets", offering several adjacent, functionally relevant binding pockets for antibiotics.
In particular, both allogeneic and autologous MSCs were shown to be targets of NK cell mediated lysis [8], [9].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com