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All residues shown to be required for threonine esterification activity are conserved.
EZH2 was also shown to be required for viability of ARMS by repressing FBX03224.
Slicer activity is also shown to be required for nuclear localization of Twi1p and for its association with Giw1p.
Recently, internalization of the EGFR was also shown to be required for mitogenic signaling via the activation of MAP kinases.
High levels of SA were detected in the mutant and shown to be required for manifestation of the snc1 phenotype.
Bax and Bak have been shown to be required for the intrinsic apoptotic pathway [6].
Swc5 has been shown to be required for histone transfer in vitro [24].
Sumoylation of HDAC1 has been shown to be required for its function.
FGF signalling has been shown to be required for the differentiation of primitive ectoderm to neurectoderm.
In mammalian cells, APC is shown to be required for the parallel array of MTs [27].
miR-155 induction by TLR4 has recently been shown to be required in Akt1 knockouts [26].
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CEO of Professional Science Editing for Scientists @ prosciediting.com