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Reactivity of cell-bound antibodies was assayed by BAT and CAST in selected patients (i) with <2 years interval between hypersensitivity reactions and present study as sensitization to drugs was shown to be lost with time [25] and (ii) without immunomodulatory medication.
MAPK10 expression has also been shown to be lost in brain tumor cell lines [ 73].
Similarly, presynapses have been shown to be lost in various models of Alzherimer's disease (Pozueta et al., 2013).
Interestingly, the interaction between NFs and tubulin was shown to be lost upon Cdk5-mediated phosphorylation of NFH [ 40].
The AIP PDE4A5 interaction was shown to be lost in the presence of AIP mutations [ Leontiou et al., 2008].
p53 has been shown to be lost or mutated in over half of human cancers (http://www-p53.iarc.fr/).
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Couples with children were shown to be losing 9.7%, while couples without children are losing 4.1%.
Hot Jupiters, due to their extreme proximities to their host stars, have been shown to be losing their atmospheres into space due to stellar radiation, much like the tails of comets.
Importantly, the human orthologue of murine KCTD11 has been shown to be frequently lost in human medulloblastoma (MB).
In over half of all of human cancers, p53 has been shown to be either lost or mutated.
The methylation of Histone H3 Lysine 9 is a modification associated with inactive chromatin and has been shown to be rapidly lost with 5-aza-dC treatment [ 37].
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