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If genetic variants which are instrumental variables for a risk factor are shown to be additionally associated with a disease outcome, then the risk factor is a cause of the disease.

Feeding related peptides have been shown to be additionally involved in the central autonomic control of gastrointestinal functions.

The stability of proneural bHLH transcription factors such as Ngn2 and MASH1 has been shown to be additionally regulated by association with their heterodimerisation E protein partners, E12 or E47 (Vosper et al., 2007).

These orexigenic (NPY, AGRP, ghrelin, MCH, Orexin-A,...) and anorexigenic (CRF, CCK, CART, GLP-1, leptin, insulin,...) peptides participating in the hypothalamic control of feeding behavior and satiety have been shown to be additionally involved in the autonomic control of gastointestinal (GI) functions like secretion and motility.

Similar(56)

Chondrocyte migration has been previously shown to be controlled additionally by growth factors and cytokines.

Similarly to PEG, PEGMA has been shown to be biocompatible and, additionally, exhibits a lower critical solution temperature (LCST) in water.

BMPs including BMP4 and BMP7 are additionally shown to be negative regulators in prostate ductal budding and branching [ 21, 22].

In cooperation with Bim, Puma was additionally shown to be involved in homeostasis of mast cells and macrophages.

The change among northern men with a low income was additionally shown to be significantly different (P < 0.01) from the non-significant negative change in the southern site.

However, in Arabidopsis, promoters of both At α-dox genes are active in anthers and the At α-dox2 promoter was additionally shown to be active in the ovaries and siliques [ 19, 28].

Physical stresses have additionally been shown to be activators for many processes of the immune system [10], [11], including the up-regulating of e.g. leukocytes, neutrophiles, granulocytes and monocytes, after acute physical stress such as high level training or competitive performances [12], [13].

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