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On her calculations, rates of marriages with a person from another European Union country have been flat in Belgium and the Netherlands since 2000 and shown only a modest rise in Spain.
This despite the fact that scientific studies have shown only a modest relationship between mental health issues and violence, "a relationship that is largely attributable to co-occurring substance abuse," wrote a team of authors led by Bernice A. Pescosolido, a sociologist at Indiana University.
However, biosimilar monoclonal antibodies provide many challenges compared with first-generation biosimilars, growth factors, and hormones, because they have shown only a modest clinical effect, and are often used in combination with other more toxic therapies, making it difficult to design studies that allow appropriate efficacy and safety assessments compared with the original products.
Consistent with this, studies using thermodynamic modelling to predict the output of multi-TF enhancers have shown only a modest impact of activator-activator cooperativity 70, 71.
Although neuroblastoma SK-N-DZ cells stably transfected with MIF antisense vector failed to grow in mice, other studies targeting MIF have shown only a modest effect on tumour growth (Ren et al, 2006).
On the contrary, other studies have shown only a modest increase in psychological distress immediately after notification of seropositivity, suggesting that adjustment does not play a major role in psychiatric morbidity at diagnosis of HIV infection [ 31].
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But underlying inflation showed only a modest gain.
Surveys published before the referendum have showed only a modest effect on consumer confidence.
Borrowing costs are low, and current projections show only a modest rise in the debt-GDP ratio over the next decade.
"Based on reported data, bank balance sheets appear healthy and loan books show only a modest deterioration in asset quality," the report said.
Economists have revised their pessimistic forecasts for the rest of the year and 2017 following a run of figures showing only a modest dip and steady rise in activity since the June 23 vote.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com