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In molecular docking study, ZE-4c have shown high binding energy for F-X.
One of the truncated sequences has shown high binding affinity with 16 fold increase in the dissociation constant, Kd (2.1 nM) compared to the original aptamer.
In addition, CDR L3 class X was evident in post-selection clones that have not shown high binding sensitivities, like SQA (E7) and COP clones (A5, A8, F3, and G12).> -wrap-foot> The canonical classes were determined using Strict Chothia SDR template [ 7, 9, 53, 63].
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Previous studies have shown higher binding affinities of DPA-713 and DPA-714 to TSPO than PK11195 using rat kidney membrane binding assays [ 13].
The tetradecapeptide bombesin (BN) shows high binding affinity for these BN2/GRP receptors.
Finally, H6 showed high binding affinity with P-gp with a high docking score.
The docking study showed high binding affinity of the designed compounds against KSP.
Results: Radiolabelling efficiency with I-125 was >91 % and the analogue showed high binding affinity and rapid internalisation.
In the present study, most of these compounds showed high binding affinities to the glucocorticoid receptor of liver cytosol.
The composites showed near complete (over 99.9%) arsenic removal within 1 ppb and suggested that these composites show high binding capacity for.
With a detection limit of 8.4 ng/mL, NI shows high binding affinity and comparable catalytical efficiency against CHT and was successfully applied for the inhibitor characterization.
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