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These bands are only shown for guidance, since not all the conditions for the asymptotic results to hold are fulfilled in our setting.
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In addition to the known role of Sdc in promoting Slit/Robo signalling, as shown for axon guidance in the nervous system (Johnson et al, 2004; Steigemann et al, 2004; Rhiner et al, 2005; Chanana et al, 2009), we now show that tracheal Sdc can also suppress Slit/Robo2 signalling.
This feature therefore seems to be common for other receptor tyrosine kinases as we have shown for the cell guidance ephrin receptor type-A2 (EphA2) (Sabet et al., 2015).
It comes as they are trying to show support for guidance counselor Ms. Fitzgerald.
These early results from rapid MRI of NSCLC patients show that, for guidance-quality imaging, the inherent contrast presented by the tumor mass and critical structures against the signal-poor lung parenchyma enables us to sacrifice SNR in order to achieve adequate acquisition speed to capture respiratory motion.
This is clearly shown in the guidance for non-clinical safety trials required by the regulatory authorities in Europe and the United States (the FDA and European Medicines Agency).
"You gave me advice, looked out for me, and showed me guidance every time I needed it.
Angioblasts (extraembryonic mesenchyme cells that differentiate into endothelium) isolated from the ROBO4 deficient embryos show behavior characteristic of cells searching for guidance and show lower amounts of active CDC42 in lysates [ 27].
See the picture below for guidance.
This is advice for a bad student who clearly shows poor guidance from the start.
Somatic mosaics bearing retinal neurons mutant for Pten also showed photoreceptor axon guidance defects, but to a notably lesser degree.
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