Exact(6)
Targeting of PS1 caused an accumulation of L1-32 (results not shown), an observation in agreement with what has been observed after overexpression of dominant-negative PS1 (D385N) (see Supplementary Figure S1) or treatment with DAPT (see Figure 3B).
There were no overt skeletal defects observed at birth in mice of any genotype (data not shown), an observation that is consistent with human PSACH patients when the clinical presentation only becomes apparent in early childhood.
qPCR analyses of sorted mouse plasma cells and B220+ splenic B cells revealed that transcript levels for Eef1a2 were below the levels of detection in both populations (data not shown), an observation consistent with earlier studies showing that EEF1A2 is normally expressed only in heart, muscle and brain.
Sequences aligned by using ClustalW showed 100% identity (data not shown), an observation consistent with the high degree of conservation of the small segment among hantaviruses (7, 25 ).
RT PCR showed that MBD3 expression is detectable in all the cell lines tested (data not shown), an observation confirmed for a selection of the colon cancer cell lines by Northern blot hybridisation of polyA+ RNA, although expression in SW480 relative to β-actin appears lower than for other cell lines.
iv) Finally, any variation observed for a given marker among the repeated experiments was only slightly affected by the quality of sequence traces (data not shown), an observation indicating the "robustness" of the method as specifically evaluated in the next section.
Similar(54)
Although Austin's cartoons showed an observation to topical events they can also be enjoyed outside of their original news context.
In addition, the model showed a trend for impact factor, where a 1 unit increment in impact factor showed an observation of 102.2% more key methodological items present.
Nonetheless the model did show a trend for funding reported as was shown with the regression for the overall quality score, where the presence of funding reported in a study showed an observation of 76.6% more key methodological items present or higher than studies without funding reported, on average.
Although figures are not shown, a similar observation holds for elutriated cells, as can be seen from the parameters in Table 1.
The ASO tests showed an unexpected observation of a significant degree of induction of TLR-related genes by one of ASOs designed for the knockdown of the Gαi2 gene.
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Justyna Jupowicz-Kozak
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