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ZD9331, a highly specific TS inhibitor that does not require polyglutamation for its activation, has shown activity in patients with refractory ovarian and colorectal cancer.
41 TMZ is an orally active alkylating agent that has shown activity in the treatment of malignant gliomas.
On the other hand, compound 5 has shown activity against HSV 1 and 2, while 24 was found to be active against HSV 1.
"Both the manufacturing (especially) and construction (to a limited extent) surveys have shown activity picking up in August after marked weakness in July, and we suspect that this will be the case for the services sector as well," he said.
Alkylating agents have shown activity in leukemia.
These polyamines have shown activity as inhibitors of ethanol appetite in the same experimental model.
Both gelatin nanoparticles and NiMOS have shown activity in systemic and oral delivery of siRNA, respectively.
NY-ESO-1 TCR-engineered T cells have shown activity in solid tumors.
The 130-nm albumin-bound formulation of PTX (nab-PTX) has shown activity in NSCLC.
Recent figures have shown activity in manufacturing, services, construction and the housing sectors all gathering pace.
AuNP-Gua has shown activity against HEK-293 but the IC50 > 30 μg/mL.
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CEO of Professional Science Editing for Scientists @ prosciediting.com