To show that initiation of membrane fusion at the poles results from PLCγ hydrolysis of PtdIns(4,5 P2 in the bound MV1 vesicles, we purified both MV1 and MV2, which were separately labelled with either the donor or acceptor fluorophore.
Our study shows that initiation of a drilling induced fracture (DIF) is best characterized by a fracture mechanics approach such as Rummel's model.
Those curves show that initiation of damage is very sensitive to the difference between Young's moduli of brick and mortar.
Our experiments show that initiation of coagulation is highly dependent on activation of small amounts of factors IXa and Xa in proximity to platelet surfaces and that these factors play distinct roles in subsequent events, leading to an explosion of thrombin generation.
Fifth, we have shown that initiation of KSHV lytic gene expression correlated with the reduction of EBV lytic gene expression (Fig. 6).
As such, these macroscopic observations show that initiation of new primordia follows a stable rhythm at each developmental stage and each branching order of the root system, whereas emergence might reach equilibrium after one week.
We have recently shown that initiation of XCI is directed by a stochastic mechanism, in which all X chromosomes in a nucleus have an independent probability to initiate XCI within a certain time-span [10].
Recent studies have shown that initiation of reprogramming requires mesenchymal-to-epithelial transition for cells with a mesenchymal status.
It has been shown that initiation of HAART before the attainment of the natural equilibrium of virus load may blunt the natural anti-HIV immune activity [ 12].
