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Primary analysis showed trials reporting surrogate endpoints to have larger treatment effects (odds ratio 0.51, 95% confidence interval 0.42 to 0.60) than trials reporting patient relevant outcomes (0.76, 0.70 to 0.82), with an unadjusted ratio of odds ratios of 1.47 (1.07 to 2.01) and adjusted ratio of odds ratios of 1.46 (1.05 to 2.04).
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The first three trials were "show trials".
Fig. 1 CONSORT diagram showing trial progress.
Fig. 1 Map showing trial location.
Let the show trials begin.
SHOW trials are not what they were.
Laura Secor on Iran's show trials.
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