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Note that the GFP specific shRNA (shR-E19) control showed specificity for the GFP tagged wild-type transcript and not the dsRED tagged mutant transcript.
The two designed primer sets showed specificity for the target 16S rRNA gene of P. histicola.
The identified proteins showed specificity for surface domains of the nanoparticles: mannan-binding lectins bound to the dextran coating, histidine-rich glycoprotein and kininogen bound to the iron oxide part, and the complement lectin and contact clotting factors were secondary binders.
In addition, a further 77 genes showed specificity for previously undefined temporal or spatial compartments.
The (CAGCG n/ CGCTG n and (CCGTA n/ TACGG n motifs showed specificity for 4DL and (CGTAG n/ CTACG n showed specificity for 4BL.
Compounds 5 (MLS000408882) and 18 (MLshowed3813) specificityifority for cancer versus normal cells (Table 3).
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Recently, sulfonamide based carbonic anhydrase inhibitors (CAI) showing specificity for CA IX have been designed.
Recent screening and design efforts have yielded novel classes of inhibitors that show specificity for the Cdc25s over other phosphatases and cause cell cycle arrest in vivo.
This review summarizes novel classes of inhibitors that show specificity for the CDC25s over other phosphatases, cause cell proliferation inhibition and cell cycle arrest in vitro but also, for several of them, inhibition of xenografted tumoral cell growth in vivo.
This may reflect differential affinity of BT10, showing specificity for RAR and not RXR sub-types.
A definitive answer on whether HNF1B variants modulate also the risk of other malignancies, or show specificity for prostate cancer, requires large sample sizes.
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