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Mosquitoes exposed to continuous light for 2 h (array "a"; Additional file 5) showed regulation of 188 genes (146 up-regulated and 42 down-regulated) in whole female mosquitoes.
1. Genes that showed differential regulation between cell-lines and show maximum regulation in at least one of the cell-lines, 2. Genes that showed regulation in the array and are known as TGF-β regulated genes in other studies.
Among the other genes that showed regulation after light pulse stimulation includes a putative gustatory receptor, which was up-regulated in the female head when compared to the male head; and two pheromone binding proteins, of which one was up-regulated and the other was down-regulated in the female head (Additional file 5).
In addition, 1,099 (33%) genes showed regulation by a specific TF.
Caveolin-1 and two other genes showed regulation in other tissues.
Some genes showed regulation specifically by benzoate, but not by low external pH.
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However, some proteins that spatially regulate mitosis and cytokinesis did show regulation as a group (Fig. 2C).
Regulators have a duty to regulate effectively, but as this research has shown, regulation can create perverse incentives to adhere to rules.
Indeed, the far majority of genes regulated by dietary unsaturated fatty acids in WT mice did not show regulation in PPARα −/− mice, indicating PPARα-dependent regulation.
It shows regulation as the cause of over $2,000 in additional costs per car during the past decade.
As our essay this week shows, regulation has responded to each crisis by protecting ever more of finance.
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