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Hormonal-positive, Her2-positive and triple-positive were more likely to show size discrepancy compared with other hormone profiles.
We have also noticed that linkages by BAC clones alone can be unreliable, since many BAC-end sequences do not map uniquely to the genome, and some BACs show possible size discrepancies when both ends map to a single contig.
Our data show that the size discrepancies leading to failed primary BCS occur across all tumour grades and that, numerically, low-grade disease is uncommon (<10% of cases).
Consistent with previous reports showing a size discrepancy between in vitro generated murine and human platelets as compared with their PB counterparts, we also found that hESC-PLTs were larger and more heterogeneous than human blood platelets in spreading assays.
A similar study discovered small size discrepancies in the brain structures known as the caudate nuclei.
Different isolation methods may account for the size discrepancies.
That study failed to show a relationship between size discrepancy and grade, although case numbers were considerably lower than reported here.
In the same study, they showed that the average size discrepancy in cases with Ki-67 staining of <10 % was greater than in cases with Ki-67 staining of >40%[39]9].
A more recent study of 174 cases of DCIS showed a correlation between increasing pathological radiological size discrepancy and the requirement for more than one operation (Chakrabarti et al, 2006).
However, results did not show a significant effect of alcohol on body size discrepancy or self-awareness, regardless of bulimic symptom severity.
"I am puzzled by an apparent size discrepancy between the [two toe bones]," Fisher said.
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