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Especially for patients with intermediate or high-risk AML, which often show relapse.
Cymelarsan® at 0.25 mg/kg and 0.5 mg/kg body weight cleared parasitemia within 24 h post treatment and none of the animals were found to show relapse throughout the 320 days of observation.
However, a few cases do show relapse after an interval of more than 5 years, and there is no recommendation on surveillance for such possible late recurrences.
Most recurrences of colorectal cancer occur within 5 years after curative resection, and the guidelines recommend a 5-year postoperative follow-up [1, 2]; however, a few cases do show relapse beyond this time period, with symptomatic and sometimes advanced stages causing severe complications.
35 Although the results of upfront treatment have improved, finally patients will show relapse or progressive disease.
About 75% of the cases affect corpus uteri and 15 20% of these show relapse and do not respond to systemic therapy [ 62].
Similar(54)
Furthermore, patients often show relapses despite treatment with conventional medication [ 6].
Seven eyes (87.5 %) in Group I did not show relapses during the follow-up periods (Fig. 5).
In our study, we have indication that some IHC-positive tumors may show relapses and do not cluster with WNT tumors by methylation profiling, although the number of investigated tumors was low.
1 patient in G1 and 2 patients in G2 showed relapse after 2 yrs.
After an average 6.7-year follow-up, 18 patients (50%%) showed relapse.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com