Sentence examples for show reduced responsiveness from inspiring English sources

Those who had episode recurrences during the discontinuation were more likely to show reduced responsiveness upon re-treatment.

Resistance to thyroid hormone (RTH) is a genetic disease associated with mutations to TRβ that lack or show reduced responsiveness to thyroid hormone (triiodothyronine).

Shb knockout endothelial cells show reduced responsiveness to VEGF-stimulation with respect to ERK (extracellular-signal regulated kinase), Akt, FAK (focal adhesion kinase), Rac1 and myosin light chain kinase [ 14, 17].

Finally, PD myoblasts showed reduced responsiveness to T stimulated mRNA expression of mTOR vs. CON cells and T also reduced myostatin expression in PD myoblasts only.

We started with a clone of rat insulinoma cells (S4 cells), which showed reduced responsiveness to glucose in terms of insulin secretion.

Although all cells responded well to IFN-β stimulation, obvious differences in dsRNA responsiveness were apparent, with 3 out of the 8 cell lines showing reduced responsiveness to poly IC) stimulation (Figure 7B), similar to that of Huh7.5.1 cells (data not shown).

In one small observational study, Somigliana et al. showed reduced responsiveness to ovarian stimulation in women with unilateral endometriomas [ 26].

Although here we observed that atypical MBCs showed reduced responsiveness to TLR4 and TLR9 ligands and other polyclonal stimuli, the extent to which this is modulated by FcRL5 expression remains to be determined.

Also, in line with the results obtained in the in vitro phosphorylation experiments, we found that a PIN3 S4A S5A variant showed reduced responsiveness to D6PK when compared to wild type PIN3 providing further support for the importance of the S4 and S5 phosphosites for PIN activation by D6PK.

Several recent imaging and electrophysiology studies also support a finding that older adults show reduced physiological responsiveness to negative stimuli, even as responsiveness to positive information, financial gains, or self-reported positive affect, may not differ across age [ 7- 9].

In support of this, our data show reduced CCL19 responsiveness in SH2D2A−/− thymocytes and Park et. al. reported that TSAd also regulates the responsiveness to RANTES [25].