In addition, flavone C-glycosides isolated from LH show potent anti-viral activity against human respiratory syncytial virus (RSV 30.
Several new derivatives were found to show potent Hh signaling inhibitory activity with nanomolar IC50 values.
It was observed that icogenin and its analogue show potent antitumor activity in vitro.
These analogs show potent (nM) activity (12a k) with a moderate selectivity.
The optimized compound 40 was found to show potent anti-HIV activity.
A set of compounds were identified to show potent antimicrobial activity together with low hemolytic activity.
Many new derivatives were found to show potent Hh signaling inhibitory activity with nanomolar IC50 values.
Compounds 15j and 15p show potent inhibitory activities in cell proliferation assays.
Cryptophycins, depsipeptides isolated from terrestrial blue green algae, show potent activity against a variety of tumor cell lines.
GSK1115 and GSK7227 show potent partial agonism of the PPARδ target genes CPT1a and PDK4 in skeletal muscle cells.
In this study, we show potent in vitro purging induced by adenosine triphosphate (ATP) for leukemic cells.
