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In general, genes in the same pathway tend to show positive interaction and those in parallel pathways show negative or synthetic lethality [ 116].
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'Filled mice' show positive interactions, and 'empty mice' show negative interactions.
Differing from ABAP1, AIP1 did not show positive interactions with proteins that are part of the pre-RC.
In the case of SPC, Fig. 7 shows positive interaction between applied potential and salt concentration.
NoWBLH1 deletion construct lacking the BEL domain showed positive interaction with WKNOX1 and WLG4.
In ER-negative disease there are now more studies showing lack of interaction than studies showing positive interaction [ 6].
All studies in our review showed positive interaction on an additive scale, which is the recommended method to assess biologic interaction [ 8, 9].
Some of these genes showed positive interaction (red in "siP1∗T" and "siP2∗T") and others showed negative interaction effects (green in "siP1∗T" and "siP2∗T") by PML knockdown and TNF α treatment.
In particular, FOXA1 showed positive interactions with ERBB2 and IGF1R while ESR1 and GATA3 were positively associated with NAT2 in both datasets.
Mixture design showed positive interactions among the enzyme components.
In our study, qDTY 1.1 showed positive interactions with qDTY 2.1, qDTY 2.2, and qDTY 3.1, whereas qDTY 2.2 showed positive interactions with qDTY 4.1, qDTY 12.1, and qDTY 3.1.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com