Residuals from the model showed marked patterning when plotted against year, violating the assumption of homogeneity.
Analysis by geographic area suggested marked patterns.
Human social contact patterns show marked day-of-week variations, with a higher frequency of contacts occurring during weekdays when children are in school, and adults are in contact with co-workers, than typically occur on weekends.
Cross-sectional studies have shown marked focal patterns of atrophy in PCA and tAD patients [14,15], suggesting that at some point during the disease atrophy changes are relatively confined to posterior regions in PCA and to medial temporal lobe regions in tAD.
These findings are central to the hybrid theory of malignancy and provide an explanation for why malignant cells show marked changes in gene expression patterns from their premalignant counterparts [2]– [4].
Despite the differences noted above, the patterns of earnings for WIA and comparison group participants show marked similarities.
Heterophyllous aquatic plants show marked phenotypic plasticity.
Macrophages show marked phenotypic heterogeneity.
Our results are in striking contrast to previous reports which showed that histone modification exon-intron marking patterns were merely a reflection of nucleosomal distribution, with well-positioned nucleosomes on exons accounting for apparent histone modification biases [19], [20], [21], [22].
NIH 3T3 cells cultured on the temporal nanopatterns showed marked alignment along the pattern direction, regardless of their ridge and groove widths.
