Sentence examples for show linkage from inspiring English sources

It is thus possible that the association seen with MM here may represent linkage to estrogen related effects, either through cross-regulation effects of the two genes or via linkage to another marker in the distal parts of ESR1 that does not show linkage to those markers we have already interrogated in this study.

For the most part, genes causing more common types of migraine have been identified from neurological, vascular and hormonal pathways and in 2010 the first functional variant to show linkage to familial MA was identified in TRESK, a potassium channel involved in neuronal excitability [10].

It has been observed that trans-eQTLs form clusters, or 'hot-spots' [19], where mRNA levels of transcripts across the genome show linkage to the same genetic locus.

This is an overly conservative number since some SNPs do show linkage disequilibrium between each other and, thus, the assumption of test independence central to the Bonferroni correction is not met.

After removing two outliers (alpha factor and niguldipine, which each show linkage with lod >40 and are nearly perfectly predicted using both transcripts and markers), we correlated prediction accuracy with linkage (e.g., lod score) when the prediction algorithm utilizes either the 200 highest-ranked features (Figure 2) or the single highest-ranked feature (Figure S1).

In this paper, we refer to genes whose expression levels show linkage coincident with their own location as cis-acting QTL and, although there appears to be a minor role for local trans-acting polymorphisms at these loci, we refer to the causative polymorphisms at these loci as cis-acting regulatory polymorphisms.

In the remainder of this work we focused on the two families that showed linkage to the same region on chromosome 16.

M.G. and N.H. performed genotyping analyses within the families and also analyzed Chinese hypertensive families that showed linkage to the chromosome 12p locus.

Three pairs of -EcoR I-CTG/Mse I-CCT, -EcoR I-CTG/Mse I-CAT, and -EcoR I-AGT/Mse I-CCC showed linkage with aphis resistance.

We have previously shown linkage of PD to chromosome 8p.

An even greater proportion of African-American families have shown linkage to HPC1.