Sentence examples for show high affinity from inspiring English sources
Similar to 7SK-SL1apical, our ITC experiments show high affinity binding of both the Tat RBD and the CycT1 Tat AFF4 complex to TAR (Kd = 22.5 ± 15.2 nM and 77.7 ± 62.7 nM, respectively), confirming previous studies that the Tat RBD significantly contributes to the interaction with TAR RNA (Fig. 5a, b, Supplementary Table 2 23,29,30.
Our previous work on pyridazinone arylpiperazine derivatives suggested some structural features that a compound should have to show high affinity and good selectivity for α1 adrenoceptors (AR) with respect to α2-AR.
The low-molecular-weight biological thiols show high affinity to the surface of AuNPs; this causes replacement of AuNPs' shells with thiol containing target molecules leading to the aggregation of the AuNPs through intermolecular electrostatic interaction or hydrogen-bonding.
Several compounds show high affinity for telomeric G-quadruplex DNA in classical and competition FRET assays, together with low duplex DNA affinity, although they do not show activity in a telomerase assay or evidence of telomere shortening.
All the compounds show high affinity for the A1 adenosine receptor, and many of them also show a good selectivity for A1 with respect to A2A and A3 adenosine receptors.
New chromogenic supramolecular vanadophiles were designed and synthesized by incorporating hydroxamic acid chains on a 1,3-alternate thiacalix[4]arene scaffold and were found to show high affinity toward vanadate ions.
In in vitro competition studies, agonists consistently show higher affinity for receptor molecules bound to G proteins ("high-affinity state") than for free receptors ("low-affinity state") [6 8].
Even though multigravid women have higher levels of antibodies against DBL5ε than primigravidae, these antibodies did not show higher affinity against this VAR2CSA domaindomain (figure 3A).
Some telomeric proteins bind specifically to dsDNA and others show higher affinity to ssDNA.
Compounds 1a-d showed high affinity for κ opioid receptor.
Most compounds showed high affinity and selectivity for S1P1 receptor.
