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Amino termini upstream of TMH-1 and carboxyl termini downstream of TMH-7 were removed as they show extreme variability in these regions.
The most divergent group is comprised of putative HI inducers such as STAND, HET-s/LopB and HET domain proteins that show extreme variability in sequence, copy number and domain composition.
Because the control regions show extreme variability across the taxa and even among closely related species, primary sequence of much of the control region does not appear to be particularly important for regulatory function [ 48].
Data collected show extreme variability in procedures and methods of compilation of this form of certification; in 3312 cases the age of the first dose was reported (median age 11.68 years); anti-HBs antibody titer was present in 759 individuals.
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The reported driving-point mechanical impedance (DPMI) characteristics of the hand arm system exposed to vibration show extreme variabilities among them at higher frequencies.
In some cases, results from experiments that showed extreme variability were excluded.
However, as with BT cancer, studies of benign BT diseases showed extreme variability in methods and findings.
Unfortunately the applied scoring systems have shown extreme variability regarding the type and individual scoring of investigated features including combination with functional tests, and outcome parameters.
A coupled nearfield and farfield model of the Mamala Bay (Oahu, Hawai'i) outfall [ 36, 37] showed extreme variability of the plume behavior due to changes in currents and density stratification with nearfield dilution from one hundred to several thousands.
The sensitivities of the AML blasts expressed as Km showed extreme variability between the patients from as much as 40-fold below (for daunorubicin) to 6,3 × 10-fold above (for ara-C) the median value (Table 2).
A similar complex and precise regulation seems to be present in humans because analysis of differential allelic expression showed extreme variability between the joint tissues with differences even between regions of the same cartilage surface in function of their proximity to the OA lesion [ 32].
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