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Mutants that reduce negative feedback considerably (CDC2438A) still show competition, with dynamics similar to wild−type (Kuo et al. 2014).
It should also be noted that although some inhibitors targeting substrate docking sites show competition with peptide or protein substrates, they are considered outside the scope of this review because they do not bind at the protein substrate phosphorylation site.
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Photo: "Fired Broncos Coach Mike Shanahan, pictured in a tooth-showing competition with John Elway, rumored to be in contention for Jets head coaching job.
In addition, all C-terminal antibodies tested by pair-wise mapping on the SPR instrument, showed competition with themselves meaning that when PrP was captured by a particular antibody, the same antibody could not bind on PrP, when injected in solution.
Since ABRC contained ABRE and Coupling Element [ 19], 2X ABRC oligo-duplex showed competition with the probe.
On the basis of its structural resemblance to tyrosine and Lineweaver Burk analysis showing competition with peptide substrate but not ATP, erbstatin was initially reported as a substrate phosphorylation site inhibitor.
The other band indicated with an S, showed competition with both an excess of unmethylated as well as an excess of methylated probe, indicating that for this particular sequence the transcription factor binds to the Sp1b probe, regardless of DNA methylation status of the CpGs within this probe.
On April 28, the singer performed "Vida" on a season eighteen episode of the American dance show competition Dancing with the Stars; he was accompanied by the show's Pro Dancers.
Bt-transgenic rice failed to show competition advantage compared with non-transgenic rice in the present study.
Figures 1A and 1C show competition between H1° and H1a with excess protein of 1.5 and 10, which yield values of H1a/H1° in the pellets of about 6 and 15, respectively.
We previously reported that toxin fragments that encompass the CROPs plus a great part of the intermediate domain show stronger competition with full length TcdA than the mere CROPs [25].
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