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However, ChRs show clear limitations, such as the small conductance.
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Bioinformatics is one important tool in functional genomics, although showing clear limitations in predicting ab initio gene structures, gene function and protein folds from raw sequence data.
However, these mechanical alignment guides have shown clear limitations in terms of accuracy and precision of proper orientation of the hip prosthesis [ 11].
The hopes for future applications of optogenetics are high, but ChR is not the optogenetic prodigy as some advertise it, as it shows clear limitations for optogenetic use: (i) Nature employs ChR for gradual membrane depolarization, resulting in small conductance and not in the all or none responses required for efficient optogenetic use.
Whereas these programs show clear strengths, their limitations have to be faced as well.
Recognising the aforementioned limitations that accompany a single-arm study design, PEP02 did show clear evidence of antitumour activity in a subset of patients in whom no standard of care therapy otherwise exists.
These results show clear patterns.
BCmicrO show clear improvement.
A notable difference between the aquatic environments and our edaphic environment is the relative inflexibility of the soil C P ratio, which only varied by a factor of 2 between the 0_0 and 30_30 soil despite showing clear signs of P-limitation.
Despite these limitations, CNV analysis showed clear tetrasomy of chromosome 1q (CN = 4) rather than the expected trisomy (CN = 3).
However, despite these limitations, we succeeded in showing clear gradients of APDs, VERPs, and EGDs, and linking these to an increased incidence of discordant alternans and earlier onset of VT at the RVOT.
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CEO of Professional Science Editing for Scientists @ prosciediting.com