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FLIM images with the corresponding false color coding (Fig. 1e, f) show a clear-cut difference between the ICC-labeled CMS and vehicle treated skin, underscoring the selective and highly sensitive detection of labeled CMS.
Our results show a clear-cut difference in the ratio type 1: type 2 transitions in ancient (1∶8) and modern (3∶1) sequences.
However, the studied population is a heterogeneous group even in the overt or non-overt DIC group; thus, the result may not show a clear-cut difference between the overt and the non-overt groups.
We used a specific methodology for calling the RH genotypes: the principle is to identify markers for which raw signal intensities show a clear-cut difference between the negative hamster control and the positive control.
An older study that utilized radiological assessment of the bone density in the second metacarpal of normal women and those with pregnancy induced hypertension using the microdensitometry method showed subtle changes in the bone size and densities at various gestations of the pregnancies, but were unable to show a clear-cut difference in the BMD between the tow groups [ 10].
However, our study focused on patients suspected of having DIC (some with a recent inflammatory insult, others with overlaying stimuli in chronic conditions, and others in recovery); thus, the result may not show a clear-cut difference between the overt and the non-overt groups.
Unfortunately our study did not show a clear cut effect of sumatriptan on the cilostazol induced headache.
Indeed, FMF had previously been addressed3 and TRAPS does not show a clear cut phenotype.
Remember, there's a clear cut difference between being a boss (a horrible one at that) and a leader.
The experiments show a clear difference between the thermomechanical responses of two TRC composites.
The damage values show a clear difference between the two considered specimen shapes.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com