The fact that this is a compound that can be given orally, that gets into the brain and prevents brain disease, is a first in itself… We can go forward and develop better molecules and I can't see why preventing this process should only be restricted to mice.
Trials must be designed with careful consideration and general agreement of inclusion/exclusion criteria for MCI, and should only be restricted to those individuals who are most likely to be affected favourably by the treatment [ 3].
It is becoming more widely accepted that therapeutic approaches in HD should not only be restricted to targeting the brain pathology but also major efforts should be made to understand the related peripheral pathologies, including those of skeletal muscles.
This effort should not only be restricted to strains that have been isolated, but also to uncultured ones that can be characterized through the use of single cell genomic (SCG) approach.
For example, access to live and recorded images should only be permitted when it is absolutely necessary and, even at that, it should generally be restricted to police officers of the same sex as the detainee.
Lately, prominent international recommendations have aimed to restrict the use of seclusion and restraint, and reminded clinicians that these measures should only be used in exceptional cases [ 8].
The prescription of antibiotics based on only tachypnoea should be restricted to settings where CXR performance is not feasible.
For example, a test that is supposed to measure the ability to calculate should not be restricted only to addition and subtraction but include all basic arithmetic operations.
The term, however, should probably be restricted only to those agricultural cultures that ritually reenact the marriage and that relate the marriage to agriculture, as in Mesopotamia, Phoenicia, Canaan, Israel (the Song of Solomon has been suggested to be a hierogamitic text), Greece, and India.
On the other hand, Polish logicians strongly insisted that logic should not be restricted only to mathematics and required the co-operation of representatives of all field in which logic might be used.
[ 9] Thus, the possibility of anxiety as a cause of respiratory symptoms should not be restricted only to patients with severe asthma.
