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Overall however, although we might underestimate the effect size of inbreeding depression, the downward bias should not be substantial, and as far as we are aware, any such effect will be independent of the environmental indices we used to test for I×E interaction.
However, because study participants all lived in the same region with no large industrial cities, the variability in the levels of air pollution between participants was not likely to be large, so the potential confounding effect by air pollutants should not be substantial in the present analysis.
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Although this policy change is very disturbing, supporters of criminal justice reform should not be discouraged: substantial criminal justice reform remains both possible and likely if advocates continue to fight.
(However it should not be understood as substantial in the western philosophical sense because it is "empty" — more on "emptiness" below).
The effect on take-up is substantial, which should not be the case if individuals were perfectly rational.This "nudge" approach works elsewhere.
Some experts contend that the West should not be concerned about a substantial Chinese presence in Iraqi oil fields, because it gives China greater stake in improving stability in the region.
Second, while complexity reduction is important, it should not be achieved at a substantial cost in bandwidth.
Even though an important issue in WZ coding is reduction in encoding complexity, it should not be achieved at a substantial cost in bandwidth.
Clearly, if this occurs in planar environments, choices for changing trajectory can only amount to movement that is either left or right, and should not be executed too early where there are substantial corner-cutting benefits to be gained by the predator.
He added, "We should not be surprised when we see substantial change in the whereabouts of marine populations or changes in their timing of breeding or migration dates," The study, whose lead author was Michael T. Burrows of the Scottish Marine Institute's Department of Ecology, appears in the latest issue of the journal Science.
29 However, it is recommended that duloxetine should not be prescribed to patients with substantial alcohol use or evidence of chronic liver disease and it should be discontinued in patients who develop jaundice or other evidence of clinically significant liver dysfunction.
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