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This suggests that, first, there is no simple decision rule that could guide which patients should and should not be commenced on MTX.
For this approach, reported doses associated with a low probability of requiring NAC could be used to define a group of patients where NAC should not be commenced prior to a paracetamol concentration being determined.
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Although local guidelines may vary, current guidelines typically state that patients should not normally be commenced on Trastuzumab if their baseline Ejection Fraction (EF) is ⩽55%.
Our findings suggest that adjuvant RT in BCS patients should not be unnecessarily delayed and certainly should not commence later than 20 weeks following surgery.
While considerable debate exists whether ART should be commenced early or late during TB treatment, there is compelling evidence that ART in eligible patients should not be deferred until after TB treatment[4].
One of the Brighton Declaration proposals says ECHR judges should not be "older than the 65 years at the date on which their term of office commences".
There are two further reasons why these devices should not be written-off (1) their unique mechanical simplicity and (2) the high probability that exploration of the cycle – and thus of power-producing potential – has barely commenced.
In a statement, the watchdogs said: "These investigations will determine whether or not any prohibition proceedings should be commenced against them.
The current study did not address routine follow-up for children with HCV infection or when treatment of HCV should be commenced.
We want to see a clear timeline and goals for this process and believe it should be commenced as soon as possible".
The fact finding investigation compiled by civil servants has recommended that a disciplinary investigation should be commenced against Mr Brimstone.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com