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Since objective assessment of histology would represent a huge leap forward in scientific measurement and clinical diagnosis, such claims should be substantiated by strong evidence.
Therefore, any claim of the biological authenticity of a modified PrP protein should be substantiated by its ability to sustain prion replication.
On the other hand, the optimal dose of metronomic epirubicin should be substantiated by modifications of the current orthotopic animal model and running clinical trials in the future.
Thus, even though multiple computational approaches were applied to crosscheck the outcome of a single tool, the findings of our study should be substantiated by experimental data in future studies.
Detection of new subtypes of picornaviruses indicates that viruses with new phenotypic traits could emerge, and conclusions on tropism of new strains should be substantiated by extensive experimental or clinical investigations (39 ).
Our results, however, suggest that exploratory spatial and spatio-temporal analysis should be substantiated by additional analyses that will take ownership or pig movement into consideration, particularly in zones where spatial clustering of premises under the same ownership exists.
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Rather, the report states that "the performance of any anchorage system should be substantiated through testing".
This is a surprising result that should be substantiated.
This assumption should be substantiated in further research.
Anyhow, these results should be substantiated in larger cohorts.
However, their presence should be substantiated in analysis of the impending genome sequence.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com