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The reused code, integrated in the target system, should be (re- validated the
An analytical method should be re-validated in case of changes in the RP preparation process that may affect the quality of the final products, when purification components are replaced by different ones (e.g. alumina cartridges are replaced by ion exchange cartridges) or the purification method is changed (e.g. HPLC vs SPE) and in other circumstances.
Therefore, the German version of the PRU should be re-validated with specialized medical doctors to evaluate its transferability.
Such modifications should only be made following approval by the local safety committee and any modified equipment should always be re-validated before use.
PRO measures should, ideally, be re-validated in each study using whatever data are available for the validation: for instance, the relation between the PRO and other related outcomes measured.
All minor modifications of the original, approved QC-method must be re-validated according to a template given in the original submission and a statistical equivalence should be shown between the original and modified QC-methods.
If the model is re-trained, it must be re-validated with a new test set.
The sock user should be re minded..
The plan should be re-examined.
should be re-interred in Australia.
I believe they should be re-run".
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com