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One issue is whether low levels of read counts qualify as a rare transcript, or whether they should be discarded due to the uncertainty in their quantification [ 2].
Another HealthTech product that has had significant impact is the Vaccine Vial Monitor, a small label that is affixed to individual vaccine vials that records exposure to heat and provides a visual indication of whether the vial can still be used or should be discarded due to too much heat exposure.
This poses the question as to whether all of these putative biomarkers should be discarded due to their expression in blood cells, or whether extensive validation and perhaps additional profiling on larger more diverse patient cohorts will confirm the most reliable biomarker candidates.
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So the results of such epidemiological studies have to be discarded due to confounding.
Undersize fish may be discarded due to the minimum landing size regulations, overquota fish can be discarded in a multi-species fishery due to quota exhaustion of one species.
Unique destruction effects for the station had to be discarded due to time constraints.
If one pair of primers resulted in multiple fragments in a particular species possibly due to gene duplication, the marker should be discarded for that species.
All other cyst fluid should be discarded.
There are times when whitespace should be discarded.
The scab should be discarded in the same way.
Any clams that, once cooked, stay closed should be discarded.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com