To do so, it should be demonstrated that the confinement approach would be capable of reducing early and late offsite doses.
In order to operate the reactor for another 10 years and more, it should be demonstrated that the irradiation embrittlement of the reactor will be adequately managed by ensuring that the fracture toughness properties are above a certain level of the required safety margin.
For the luciferase assays, it should be demonstrated that the mRNAs are intact and equivalently abundant.
The neurons need to be synaptically isolated, and ideally it should be demonstrated that the intrinsic discharge can be reset or somehow be altered by current injections.
For FGF23 level to be clinically useful, it should be demonstrated that FGF23 is a risk factor for the clinical outcomes of CKD, and the target FGF23 level for the prevention of such clinical outcomes should be determined.
5) It should be demonstrated that the chemLTP protocol indeed works, i.e. potentiates EPSC amplitude and that endogenous AMPARs shift after successful LTP induction from TC10/Arf6 to clathrin.
On the other hand it should be demonstrated that the number of deposition cycles plays a minor role for the nanofibers' spectral emission, whereas Δ d p -6P represents the key parameter to tune the spectral contribution of 6T.
Similarly, for the validation of newly generated iPSC lines, genomic fidelity should be estimated, minimally at G-banding resolution, and it should be demonstrated that there is no major difference in iPSC quality between individuals (for example, by quantitative analysis of transgene silencing and pluripotency marker expression).
Briefly, it should be demonstrated that contemporary adaptive evolution has occurred within the native range, and that it leads to native populations with higher fitness in a new, human-altered habitat relative to a naïve native population that has not experienced that habitat.
To paraphrase my previous summary of that issue, in order to support the importance of this work investigating the function of the Aven RGG box, it should be demonstrated that the RGG box is required for the anti-apoptotic (or other) biological functions of Aven in affecting cancer progression.
