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We are unable to answer the question of how many studies should be considered large enough for a NMA with multiple outcomes.
For instance, as described above, we observed an average FST of 0.169 between the North and East populations of aye-aye, but without corresponding numbers from other data sets, it is unclear whether this value should be considered large or small.
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Therefore, in designing the well spacing based on the calculated X f, the actual well spacing should be considered larger than the one determined from RTA.
Given the rarity of the mutation and the hypothesized large effects on the brain, these should be considered relatively large sample sizes.
Percutaneous endovascular procedures should be considered in large infarction of the kidney.
Additional imaging of the abdomen/pelvis should be considered for large tumours of high grade in deep locations or in those with clinical signs warranting further investigation.
Since cloud computing environments adapt virtualization technology [20], scalability should be considered enabling large-scale distribution [21].
The following three constraints should be considered in large-scale image retrieval applications: search accuracy, efficiency, and memory usage [8].
Normalization for gestational age should be considered in larger series.
Our results suggest that dose escalation should be considered for larger and/or metastatic lung tumors to improve the balance of benefits and risks of SBRT and to obtain better overall survival.
Generalisation to a broad range of racial groups should be considered when conducting large international trials of stroke therapy.
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