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From our study it is evident that QTLs can be systematically searched to identify possible candidate genes responsible for disease by using a combination of in silico methods, although it should be cautioned that gene selection at any given time would be based on genes already known or suspected to be involved in tumorigenesis.
However, readers should be cautioned that little correlation between the level of sequence similarity and the structural similarity of their substrates has been observed for these protein families [ 80].
It should be cautioned that the comparisons are not quite apples to apples.
Some even have forums where students can ask questions (although students should be cautioned that these sources might not always have the most up-to-date information).
Swimmers should be cautioned that salt water and heavily chlorinated pools may irritate the cornea if the eyes are kept open underwater.
Clients should be cautioned that courts have been critical of actions that appear to be attempts merely to harass and intimidate anonymous posters rather than to obtain judicial redress.
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It should be cautioned, however, that the fidelity of chemical NOS inhibitors is imperfect.
It should be cautioned however, that despite promising results in cellular models, in vivo data are still limited.
It should be cautioned, though, that the effect of mutant p53 on PI3K/AKT signaling is not limited to only p53-R273H mutants.
It should be cautioned, however, that l-arginine may have effects unrelated to NOS activity (Hentall, 1995; Rivadulla et al., 1997).
It should be cautioned however that experiments from two independent laboratories have failed to confirm the presence of natively unfolded α-synuclein tetramers in PD [ 31, 32].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com