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1, 2, 33 Furthermore, in some instances, the tumor regressive response to neoadjuvant chemoradiotherapy by intraoperative histopathologic evaluation may have influenced the decision of the surgeon to accept the shorter margin or to convert to APR.
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By a short margin, the results obtained from the model called the autocatalytic comproportionation seem to explain the experimental data better than the other model called the competitive nucleation.
I did not get to the top by a very short margin - about 900 meters - which is like two laps around a high school track -- and I did not die.
Two studies showed statistically significantly higher actuarial local recurrence rate in the short margin group compared to the long margin group.
In the remaining 15 studies the difference in local recurrence rate between the short margin group and to the long margin group was not significant in univariate analysis.
During the analysis, we also observed that patients undergoing AR in the short margin groups were frequently described to have more favorable tumors than patients undergoing AR in the long margin groups or than patients undergoing APR.
Lack of any of the this information indicates that the relevant data were not provided cOnly anastomotic recurrences are described dOnly N0 patients were studied Of the eight reports showing long-term survival, survival did not differ statistically between the two groups in seven; in one remaining study survival was lower in the short margin group compared to the long margin group (Table 1).
With cash short, margins are extremely tight, which encourages corner-cutting.
In short, margins have been squeezed, and over half of the country's gold is now produced at a loss or just above break even.
This resulted in a selection of favorable tumors for AR with short margins and unfavorable tumors for APR or for AR with long margins.
As a result of the inherent bias produced by a selection process that favored patients with short margins, the question of whether a short distal bowel margin per se jeopardizes oncologic safety cannot be answered.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com