Sentence examples for shortened life span from inspiring English sources

However, not every DNA repair deficiency creates exactly the predicted effects; mice deficient in the NER pathway exhibited shortened life span without correspondingly higher rates of mutation.

The loss of Asxl2 activity results in partial embryonic lethality, shortened life span of adult animals, and a reduction in size and body weight.

The expression of mutated TTR, but not wild-type TTR, caused a complex phenotype partially reminiscent of the human pathology, which included shortened life span, neurodegeneration and early locomotor dysfunction.

Analysis of the life span of Drosophila C3G deficient adult flies indicates a considerably shortened life span, with a survival rate of 50% after 9 days at 29°C, as compared with 26 days in controls (Figure 2A and B).

Notably, dietary restriction shortened life span in more strains than those in which it lengthened life.

Shortened life span of the red blood cells is due to the increased mechanical fragility of the cell membrane.

This leads to accelerated aging and shortened life span due to growth impairment, lipodystrophy, dermal and bone abnormalities, and cardiovascular alterations.

For example, adult-specific over-expression of fruMA and dsxF shortened life span to a similar extent in males and females.

Animals injected with stable PGE2 analog and cAMP phosphodiesterase inhibitor had shortened life span both in the absence and presence of DNR treatment.

The Guarente team had discovered that a group of related genes called SIR2, SIR3, and SIR4 influenced aging in yeast; when mutated, each shortened life-span.

However, compared to Rps27l +/+ ;Trp53 +/− and Rps27l +/ − ;Trp53 +/− mice, Rps27l−/− ;Trp53 +/− mice had a significantly shortened life-span.